DUTCH Complete

The DUTCH test, which uses dried urine, is the simplest, most elegant and informative test for Sex & adrenal hormones with metabolites and diurnal patterns.

The test is done four times in a day, and the strips are then used to give you a complete hormone panel, including metabolites, effectively replacing multiple testing methods.

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Precision Analytical DUTCH complete – Comprehensive assessment of sex & adrenal hormones

DUTCH complete is a comprehensive assessment of sex and adrenal hormones and their metabolites. It also includes the daily, free cortisol pattern, organic acids, melatonin (6-OHMS), and 8-OHdG (oxidative damage to cells).

This will give you extended knowledge about your hormonal balance including additional biomarkers that point to specific vitamin deficiencies or problems with neurotransmitters (serotonin, dopamine) and damage caused to cells by oxidative stress.

Millions of women and men suffer from hormonal imbalances. Whether it is menopause, weight gain, fatigue, low libido, erectile dysfunction, premenstrual symptoms (PMS), mood swings, depression, hair loss, sleeping troubles or increased prostate cancer risk, these symptoms can lead to more serious problems if misdiagnosed. By identifying the root cause, the chronic health issues are certainly correctable, but only if properly diagnosed.

The DUTCH test was created to provide insight into many of these concerns, working to deliver the most complete assessment of sex and adrenal hormones, along with their metabolites, in one easy to administer test.

What markers are being tested within DUTCH complete?

DUTCH complete will provide you with the following markers:

  • Sex hormones like progesterone, estrogens, testosterone, DHEA and many others including their metabolites and clearance rate.
  • Adrenal hormones like total and free cortisol, cortisone, DHEA and their diurnal rhythms and metabolites.
  • Other markers that will identify how your body is using certain vitamins, processing neurotransmitters and fighting off oxidative damage.

For the complete list of markers see the section “Type, Markers & Sample results”.

Why DUTCH test is the best option for hormone testing?

DUTCH stands for Dried Urine Test for Comprehensive Hormones. This test was developed by the Precision Analytical Founder & President Mark Newman, with the goal to make a precise hormonal test with maximal interpretation value and would be easy for the patient to collect.

DUTCH complete is a clinically validated test that surpasses other hormonal test in every measure. It has the characteristic of both the 24 hour urine and salivary test but combines it in a easy to collect dried urine test. All you need to do is to urinate on 4 or 5 collection papers in the course of 24 hours, dry them and send them back to the laboratory in a standard envelope.

DUTCH vs. Saliva Testing

While the free cortisol pattern in saliva has clinical value, there is a significant missing piece to surveying a patient’s HPA-Axis function with saliva testing – measuring cortisol metabolites. To properly characterize a patient’s cortisol status, free and metabolized cortisol should be measured to avoid misleading results when cortisol clearance is abnormally high or low. Likewise with sex hormones, measuring estrogen and androgen metabolites gives a fuller picture for more precise clinical diagnosis of hormonal imbalances and HRT monitoring. Also DUTCH test will give you the hormone levels over 24 hours period while salivary testing will not.

DUTCH vs. Serum Testing

While the most universally accepted testing is serum testing it is lacking in some areas. Adrenal hormones cannot be effectively tested in serum because free cortisol cannot be tested throughout the day. There is also a lack of extensive metabolite testing (especially for cortisol and estrogens). Cortisol clearance from the body is very rapid with the half life of only 66 minutes. Also the diurnal rhythm is somewhat specific as it spikes hard (about 4 fold of normal) about 45 minutes after waking up. Imagine taking your blood during the spike or just an hour later, or after a stressful situation… You just can’t get the timing right with a cortisol sample. DUTCH measures all the cortisol (including cleared) so you will always get accurate results.

DUTCH vs. 24-Hour Urine Testing

There are two primary drawbacks to 24-hour urine testing of hormones. First, the collection is cumbersome, and as many as 40% of those who collect, do so in error. Secondly, dysfunction in the diurnal pattern of cortisol cannot be ascertained from a 24-hour collection. Some providers add saliva for daily free cortisol. DUTCH eliminates the need for two tests.

Completing the test

This test is extremely easy to do. No blood to draw, spitting in tubes or filling up jugs of urine. All you need to do is urinate a few times on the included collection papers, mark the samples with your name, date and time and send them back to the lab by regular mail.

The dried urine samples are very stable and will not degenerate even after 3 weeks on room temperature.

This test is suitable for you if you would like to know more about your hormonal balance.

It is best suited for issues like:

  • Menopause difficulties
  • weight gain
  • fatigue
  • low libido
  • erectile dysfunction
  • premenstrual symptoms (PMS)
  • mood swings
  • depression & anxiety
  • hair loss
  • sleeping troubles and insomnia
  • prostate, breast, ovarian cancer
  • burnout
  • HPA axis disorder and Adrenal fatigue
  • Low energy
  • Alzheimer’s dementia
  • Low immune system
  • PCOS
  • Hormone Replacement Therapy assessment (HRT)

Type, Markers & Sample results

Sample Result-Male                         

Sample Result Female

What kind of test is this?

This is a dried urine test.

What markers are being tested?

Progesterone Metabolites

  • b-Pregnanediol
  • a-Pregnanediol

Androgen Metabolites

  • DHEA-S
  • Androsterone
  • Etiocholanolone
  • Testosterone
  • 5a-DHT
  • 5a-Androstanediol
  • 5b-Androstanediol
  • Epi-Testosterone
  • 5α-Reductase Activity

Estrogen Metabolites

  • Estrone (E1)
  • Estradiol (E2)
  • Estriol (E3)
  • 2-Hydroxyestrone (2-OH-E1)
  • 4-Hydroxyestrone (4-OH-E1)
  • 16-Hydroxyestrone (16-OH-E1)
  • 2-Methoxyestrone (2-Methoxy-E1)
  • 2-Methoxyestradiol (2-Methoxy-E2)
  • 2-Hydroxyestradiol (2-OH-E2)
  • 4-Hydroxyestradiol (4-OH-E2)
  • Methylation-activity
  • 24 hour cortisol
  • 11b-HSD index (coltisol/cortisone balance)

Cortisol and Corticone

  • Diurnal Pattern of Free Cortisol
  • Diurnal Pattern of Free Cortisone
  • a-Tetrahydrocortisol (a-THF)
  • b-Tetrahydrocortisol (b-THF)
  • b-Tetrahydrocortisone (b-THE)
  • Metabolized Cortisol (THF+THE)

Organic Acids

  • HVA (Homovanillic acid)
  • VMA (Vanillylmandelic acid)
  • KYNA (Kynurenic acid)
  • MMA (Methylmalonic acid)
  • Xanthurenate
  • Pyroglutamate
  • 8-OHdG (8-Hydroxy-2-deoxyguanosine)
  • Melatonin (6-OH-Melatonin-Sulfate)